Candida Dubliniensis

What is Candida Dubliniensis?


Candida Dubliniensis is a fungal pathogen which is originally isolated from patients who have been affected with AIDS. The fungus is also isolated from immune competent patients. This kind of Candida is also closely related to Candida albicans. But, they form phylogenetic cluster that can be found in DNA fingerprinting.


Candida Dubliniensis
Candida Dubliniensis

In a recent study, the prevalence of Candida Dubliniensis in the Candida bloodstream isolates was performed. In total, 368 isolates of Candida dubliniensis were identified, with 67.1% detected from respiratory specimens, 11.7% oral swabs, 9.2% urine, 3.8% blood, and 2.7% from vaginal swabs. It also definitely highlights a greater role of Candida dubliniensis in bloodstream infections which have been recognized. The prevalence of Candida dubliniensis fungemia is unknown due to the inability to distinguish the species from similar species Candida albicans. The study concludes that fluconazole was most effective in cases to treat cases of Candida dubliniensis. However, there was also some resistance seen to fluconazole in some patients as well. Overall, the findings of this study suggest that fluconazole can prove to an effective drug to help treat most cases of Candida dubliniensis, and that respiratory specimen testing is the most efficient method for detecting Candida dubliniensis. Due to the high success rate from the respiratory specimen test results it may also be a great method to check for other forms of Candida species as well.


In the Journal of Clinical Microbiology, a study in 1998 found the presence of Candida Dubliniensis from the oral test results of 27% HIV patients and 32% of patients with AIDS, all with clear signs of oral Candida. The findings of this study suggest that HIV and AIDS patients are more prone to Candida infections like Candida Dubliniensis, and that other illnesses that weaken the immune system like diabetes, leukemia, hepatitis and cancer are more susceptible to developing this infection.


Symptoms and Causes for Candida

To have a better understanding of Candida Dubliniensis you need to know the symptoms and causes of Candida albicans.


Some of the symptoms of Candida include:

  • Skin and nail infections generally occur including athlete’s foot.

  • Sometimes the person will feel tired and strained without reason or cause.

  • The person will experience constant problems in digestion including constipation and diarrhea.

  • Diseases like Hashimoto’s thyroiditis, rheumatoid arthritis, psoriasis, lupus, multiple sclerosis, ulcerative colitis, and scleroderma can occur.

  • The person experience difficulty in concentrating, has bad memory, cannot focus, and Attention deficit hyperactivity disorder (ADHD).

  • Skin problems like eczema and rashes can happen.

  • The person will feel irritable and have mood swings.

  • The individual has vaginal infections and urinary tract infections.

  • There will be seasonal allergies and ear pain.

  • The individual has cravings for consuming chocolates.


Few of the causes of Candida include:

  • The person has an immune system that is weak which is found in people above the age of 50.

  • If the individual has diabetes and the hormone level in the body is decreased.

  • If one is obese or overweight weight

  • If he/she  has underactive thyroid gland where hormones are not generated

  • If there is inflammatory disorders in the body.

  • The person works in moist conditions like in rivers and oceans

  • Usually pregnant women can be affected


Invasive Yeast Infections Causes

Invasive yeast infection occurs when the yeast fungus enters the bloodstream, and causes infection in various organs of the body. This may occur when the fungus is able to overwhelm the body’s immune power, and launch an attack throughout the body. It may also enter the bloodstream via contaminated medical equipments or devices such as the intravenous catheters.
Hopefully, the answer to the question that what causes a yeast infection invasively has been amply answered here, but there can be a number of other causes. The causes are varied just as much as the types of yeast infections that can affect the human body.


For the treatment of Candida Dubliniensis proper food habits are suggested. Since Candida grows inside the digestion system, you will want to ensure that you consume more healthy foods. Alcohol and sugar food items should be completely avoided as these beverages rapidly multiply the growth of Candida within the body.


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The quantity of carbohydrates has to be reduced. Foods which are high on carbohydrates including breads, pasta, and cakes should be avoided or taken in small amounts. However, you can consume vegetables like cauliflower, green beans, broccoli, spinach, asparagus, cabbage, turnips, peppers, kale, celery, Chinese cabbage and mustard greens.


The amount of salt taken counts and when it is taken in large quantities, then serious health problems can happen. Salt is required for absorption and digestion. You will want to also know that it is the first enzyme in the mouth. Processed salt cannot be considered good because they consist of many harmful substances. The ocean sea salt which is unprocessed, hand-harvested, certified and contains a natural balance of minerals can be considered.


Natural treatments are also effective and in most cases show antifungal effects on the Candida. One should look to consume a glass of water mixed with 2 tablespoon of apple cider vinegar twice a day, and implement plain unsweetened yogurt and raw honey to their diets as well.


If you’re not sure if you do have Candida yeast infection or not, it would be best to consult a doctor and get some tests done to confirm the presence of Candida overgrowth. Normally tests like respiratory specimen test, stool test, blood test, and urine tests are recommended. These tests can help you find out if you have developed the disease or not. The problem about Candida Dubliniensis, is that there is little or not much information about it. Unless proper tests and procedures are followed, it can be very difficult to say the kind of disease you have contracted. The antifungal medication: ‘fluconazole’ is usually given to patient with Candida Dubliniensis, but sometimes are cases of resistant to this drug as well.


Candida dubliniensis: Characteristics and Identification – Journal of Clinical Microbiology – 1998 – By Derek Sullivan and David Coleman
Candida dubliniensis: An Appraisal of Its Clinical Significance as a Bloodstream Pathogen – Plos one journal – 2012 – by Ziauddin Khan, Suhail Ahmad, Leena Joseph, Rachel Chandy
Candida: Comparative and Functional Genomics
Book By: Christophe d’. Enfert & ‎Bernhard Hube
Published: 2007
Clinical Mycology
Book By: William E. Dismukes & ‎Jack D. Sobel
Published: 2003
Comparative Analysis of the Filamentous Growth Regulators
Book By: Leanne O’Connor
Published: 2009
Essential Microbiology for Dentistry
Book By: Lakshman Samaranayake
Published: 2011


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